• Case Studies

Optimization of droplet dispersion mixing


The interfacial surface area in liquid-liquid dispersion controls the mass transfer between the phases. The surface area is determined by the droplet size of the dispersed phase. A selection of impeller designs and mixing speeds is tested to study the effect of these parameters on droplet size.


A Pixact Droplet Monitoring (PDM) system is installed on a 2-liter test reactor equipped with a side inlet. The same setup can also be used for production-scale reactors. The dispersion consists of organic solvent (50 %) and water (50 %).


The measured droplet size distribution can be used to select an optimal impeller design and mixing speed for the production-scale process. In production scale, PDM can be used to adjust droplet size distribution by controlling mixer speed and the component feed to the reactor.

Process parameters

Dispersion Liquid-liquid
Size distribution 50…1000µm
Concentration 50-50 %
Temperature 25°C
Pressure Atm