Pixact Crystallization Monitoring
The Pixact Crystallization Monitoring (PCM) technology is designed for the online measurement of industrial crystallization processes. PCM combines in-situ process microscopy with advanced image analysis techniques to produce reliable real-time information on the process.
PCM provides a live camera view of the process and detailed measurement data on crystal characteristics, such as size distribution, morphology and concentration.
Equipped with flexible installation mechanics, PCM can be fitted into a variety of applications from laboratories to manufacturing scale reactors.
Results produced by PCM
Crystallization processes can be broken down into four stages: pre-seeding (feed liquor), seeding, growth and the final state. PCM is used for measuring and controlling crystallization processes from the very beginning until the end of each batch:
Measurement results produced by PCM include:
The real-time measurement information produced by PCM is used for the efficient analysis, control, optimization and troubleshooting of crystallization processes. With the help of the system the yield and capacity of the process can be increased and quality variations in the final product can be minimized.
For the operator, PCM provides tools for
To increase productivity and promote Best Practice methods, PCM can be used in production development for
PCM measurement hardware and software
The PCM hardware consists of a Pixscope probe and a Pixstation main unit
The measurement probe showcases modular design, which allows the system to be fitted into a wide variety of applications from laboratory to production scale reactors. The probe can be installed on a port on either the side or the top of the reactor. Contact Pixact for more information on installation options.
The Pixstation main unit includes a computational unit and an automation interface. The cabinet is IP67-rated and can be installed in the production space and other demanding environments. The unit can also be customized with optional features, such as a monitor for local operation or a complete selection of automation interfaces. The design supports both fixed and mobile installations.
The PCM software is an all-in-one tool for analyzing and reporting measurement data
The PCM software controls the entire measurement procedure from data acquisition to the reporting of results. It can be used as both a fully automated online measurement software and an effective R&D tool with access to all necessary settings as well as manually controlled data acquisition and analysis.
Key features of the software
User-friendly adjustment of imaging parameters
Powerful analysis algorithms
Flexible reporting tools
In addition to the live view of the process, the Pixact Crystals software displays numerical values, trends and distribution plots for the parameters measured on the screen.
The Pixact Crystals software automatically generates a detailed measurement report for each batch or time period defined by the customer. In addition to numerical data, the report contains trends for selected results and time-stamped images of the process.
Optical configuration options
Image area [mm]
Image resolution [µm/pix]
Measurement range [µm]
Online measurement system for the real-time analysis of crystallization processes
Direct optical imaging of crystal suspensions accompanied by proprietary image processing and analysis techniques
8.5 x 7.0
4.3 x 3.5
2.1 x 1.8
All system components 24VDC, power supply unit 230VAC/50Hz
Profibus, Modbus, Analog (mA, V), Digital (5-24VDC)
IP67, ATEX on request
Min. 25mm, standard 31mm
Max. 300mm, standard 100mm
1-20mm (fixed, not adjustable)
Stainless steel AISI316L (other materials on request)
Sapphire or borosilicate
NBR, PTFE, FPM, EPDM, silicone
Directly on the process equipment using DN25 or larger fittings. Custom adapters for existing inlets can be delivered. Note that all magnifications are not available for all installation options.
Max. operating pressure
Probe head: -20C to +120C
Housing: -20C to +85C (cooling options available)